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Home Antibody All anti-GLE1 antibodies

Anti-GLE1 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA306700 Rabbit Polyclonal Gle1 Antibody 100ug $325 3-7 Days
LC423996 GLE1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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Also for GLE1 (NM_001003722)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenGle1 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human Gle1.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 - 2 ug/mL, ICC: 2.5 ug/mL, IF: 5 ug/mL
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameGLE1, RNA export mediator
Alternative NameGLE1L|LCCS|LCCS1|hGLE1
Database LinkNP_001003722
Entrez Gene 2733 Human
Entrez Gene 74412 Mouse
Entrez Gene 362098 Rat
FunctionThe proper expression of gene products in eukaryotic cells relies on efficient transport of mRNA molecules out of the nucleus. Gle1 is an essential mRNA export factor in both human and yeast cells. It associates with the nuclear pore complex (NPC) through hCG1 and NUP155 in mammalian cells and in conjunction with inositol hexakisphosphate (IP6), stimulates Dbp5, a member of the DEAD-box helicase family, triggering mRNP remodeling and facilitating RNA export from the nucleus. Recent evidence suggests that mutations in Gle1 causing defects in mRNA export can result in human disease. At least three isoforms of Gle1 are known to exist.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of Gle1 in mouse brain tissue lysate with Gle1 antibody at (A) 1 and (B) 2 ug/ml.

IHC Image
Immunohistochemistry of Gle1 in mouse brain tissue with Gle1 antibody at 2.5 ug/ml.

IF Image
Immunofluorescence of gle1 in mouse brain tissue with gle1 antibody at 5 ug/mL.


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