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Home Antibody All anti-NUP160 antibodies

Anti-NUP160 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306614
  • Rabbit Polyclonal NUP160 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC414702) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
IHC(1)
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Also for NUP160 (NM_015231)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenNUP160 antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human NUP160.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 0.5 - 1 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens nucleoporin 160kDa (NUP160)
Alternative NameDKFZp686M14102; MGC150678; MGC150679
Database LinkNP_056046
Entrez Gene 23279 Human
Entrez Gene 59015 Mouse
Entrez Gene 311182 Rat
FunctionThe nuclear pore complex (NPC) is a protein assembly localized at the nuclear rim and mediates macromolecular transport between the nucleus and the cytoplasm. The mammalian nucleoporin (NUP)-160 is part of the hetero-oligomeric complex that also contains NUP107, NUP133, NUP96, and mammalian homolog of yeast sec13p. While the majority of the NUP107-160 nuclear pore sub-complex localizes to the nuclear pore, a small fraction is observed at kinetochores and pro-metaphase spindle poles in mitotic cells in association with proteins such as Mad1, Mad2, Bub3 and Cdc20. Immunodepletion of the NUP107-160 complex resulted in defective spindle assembly indicating that it has multiple functions. NUP160 has recently been identified as an HIV dependency factor (HDF), suggesting that NUP160 may be an important drug target in HIV treatment. Multiple isoforms of NUP160 are known to exist.
Related Pathway
Cell cycle

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of NUP160 in rat brain tissue lysate with NUP160 antibody at (A) 0.5 and (B) 1 ug/ml.
IHC Image
Immunohistochemistry of NUP160 in human brain tissue with NUP160 antibody at 2.5 ug/ml.

 

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