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Home Antibody All anti-GDF6 antibodies

Anti-GDF6 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA306608 Rabbit Polyclonal GDF6 Antibody 100ug $325 In Stock
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WB(1)
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Also for GDF6 (NM_001001557)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenGDF6 antibody was raised against a 17 amino acid peptide near the carboxy terminus of the human GDF6.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens growth differentiation factor 6 (GDF6)
Alternative NameBMP-13; BMP13; CDMP2; KFM; KFS; KFS1; KFSL; LCA17; MCOP4; MCOPCB6; SCDO4; SGM1
Database LinkNP_001001557
Entrez Gene 392255 Human
Entrez Gene 242316 Mouse
Entrez Gene 252834 Rat
FunctionGrowth differentiation factors (GDFs) are members of the transforming growth factor (TGF) superfamily that is involved in embryonic development and adult tissue homeostasis. Both GDF6 and GDF7 are closely related to GDF5 which has been shown to induce activation of plasminogen activator, thereby inducing angiogenesis. It is predominantly expressed in long bones during fetal embryonic development and is involved in bone formation. In Xenopus, GDF6 is expressed at the edge of the neural plate and within the anterior neural plate including the eye fields. GDF6 is required for normal formation of some bones and joints in the limbs, skull, and axial skeleton. It may regulate patterning of the ectoderm by interacting with bone morphogenetic proteins (BMPs), and control eye development. Mutations in this gene result in colobomata, which are congenital abnormalities in ocular development, and in Klippel-Feil syndrome (KFS), a congenital disorder of spinal segmentation.
Related PathwaySecreted ProteinDruggable Genome TGF-beta signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of GDF6 in SK-N-SH lysate with GDF6 antibody at (A) 0.5 and (B) 1 µg/ml.
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