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Home Antibody All anti-GRTP1 antibodies

Anti-GRTP1 Antibody

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SKU Description Amount Price Availability*  
TA306569 Rabbit Polyclonal GRTP1 Antibody 100ug $325 3-7 Days
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WB(1)

OriGene Data

ImmunogenGRTP1 antibody was raised against a 16 amino acid peptide from near the center of human GRTP1.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB Suggested DilutionsWB: 1 - 2 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens growth hormone regulated TBC protein 1 (GRTP1), transcript variant 1
Alternative NameTBC1D6
Database LinkNP_078995
Entrez Gene 79774 Human
Entrez Gene 66790 Mouse
Entrez Gene 361180 Rat
FunctionGrowth hormone regulated TBC protein 1 (GRTP1) was identified through microarray analysis as a gene whose expression is regulated by growth hormone (GH). It contains the TBC signature motif of GTPase activator proteins of Rab-like small GTPases. GRTP1 mRNA is expressed at highest levels in testes, and is also present in kidney, lung, liver, and intestine. Administration of GH to mice resulted in an increase in GRTP1 mRNA in testes, but a decrease of GRTP1 mRNA in kidney and liver (1). GRTP1 was identified as an HIV dependency factor (HDF), suggesting that GRTP1 may be an important drug target in HIV treatment. At least three isoforms of GRTP1 are known to exist; this antibody should recognize all isoforms.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of GRTP1 in SK-N-SH cell lysate with GRTP1 antibody at 1 µg/ml in the (A) absence and (B) presence of blocking peptide.
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