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Home Antibody All anti-NPTX2 antibodies

Anti-NPTX2 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306565
  • Rabbit Polyclonal NPTX2 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC419275) , 20ug
100ug 325 In Stock
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WB(1)
IHC(1)
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Also for NPTX2 (NM_002523)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenNPTX2 antibody was raised against a 16 amino acid peptide near the center of the human NPTX2.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat ConcentrationLot Dependent
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1 - 2 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens neuronal pentraxin II (NPTX2)
Alternative NameNARP; NP-II; NP2
Database LinkNP_002514
FunctionNeuronal pentraxin (NPTX) 2 was initially identified as a member of the pentraxin family having high homology to NPTX1. Unlike NPTX1 however, NPTX2 is expressed in testes, pancreas, liver, heart, skeletal muscle as well as brain. NPTX2 possesses the lectin properties common to the pentraxin family, promotes neurite outgrowth, and is rapidly regulated by neuronal activity. NPTX1 and NPTX2 form heterocomplexes that contribute to both activity-independent and –dependent excitatory synaptogenesis. Recently, NPTX2 has been found to be highly upregulated in Parkinsonian substantia nigra and localizes to Lewy bodies and Lewy neurites in sporadic Parkinson’s disease (PD), suggesting that it is involved in the pathway dysregulation that underlies PD. This NPTX2 antibody is predicted to be specific to NPTX2 and not recognize NPTX1.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of NPTX2 in mouse brain tissue lysate with NPTX2 antibody at (A) 0.5 and (B) 1 ug/ml.
IHC Image
Immunohistochemistry of NPTX2 in human brain with NPTX2 antibody at 5 ug/ml.

 

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