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Home Antibody All anti-AIFM3 antibodies

Anti-AIFM3 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA306551 Rabbit Polyclonal AIFM3 Antibody 100ug $325 3-7 Days
LC422714 AIFM3 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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Also for AIFM3 (NM_001018060)
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OriGene Data

ImmunogenAIFM3 antibody was raised against a 16 amino acid peptide from near the center of human AIFM3.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB Suggested DilutionsWB: 1 - 2 ug/mL
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target Nameapoptosis inducing factor, mitochondria associated 3
Alternative NameAIFL
Database LinkNP_001018070
Entrez Gene 150209 Human
Entrez Gene 72168 Mouse
Entrez Gene 303786 Rat
FunctionApoptosis, also known as programmed cell death, plays major roles in development and normal tissue turnover in addition to tumor formation. Recently a protein similar to the apoptosis-inducing factor (AIF) was cloned and designated AIFL (also known as AIFM3). AIFM3 is expressed ubiquitously and is predominantly localized to the inner membranes of mitochondria. Unlike AIF, AIFM3 does not translocate to the nucleus upon induction of apoptosis. However, overexpression of AIFM3, like AIF, induced cytochrome c release from the mitochondria, cleavage of caspase 3, and ultimately apoptosis, indicating AIFM3 induces apoptosis through caspase activation. Multiple isoforms of AIFM3 are known to exist.
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of AIFM3 in human brain tissue lysate with AIFM3 antibody at (A) 1 and (B) 2 µg/ml.


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