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Home Antibody All anti-FGF4 antibodies

Anti-FGF4 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306516
  • Rabbit Polyclonal FGF4 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC419590) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
IF(1)
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Also for FGF4 (NM_002007)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFGF4 antibody was raised against a 18 amino acid peptide near the carboxy terminus of the human FGF4.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsELISA, WB: 0.5 - 1 ug/ml, ICC: 2.5 ug/ml, IF: 2.5 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens fibroblast growth factor 4 (FGF4)
Alternative NameHBGF-4; HST; HST-1; HSTF1; K-FGF; KFGF
Database LinkNP_001998
Entrez Gene 2249 Human
Entrez Gene 14175 Mouse
FunctionFibroblast growth factor 4 (FGF4) is a member of the fibroblast growth factor (FGF) family that possess broad mitogenic and cell survival activities and play key roles in growth and survival of stem cells during embryogenesis, tissue regeneration, and carcinogenesis. FGF4 was identified by its strong oncogenic transforming activity and is a potent angiogenic factor, expressed in several highly vascularized tumors and also in adult mouse testis, intestine, and brain. Studies on the mouse homolog suggests a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway. Furthermore, FGF4 regulates neural progenitor cell proliferation and neuronal differentiation. Recent studies show a growth-promoting role for FGF4 in human embryonic stem cells and a putative feedback inhibition mechanism by a novel FGF4 splice isoform that may serve to promote differentiation at a later stages of development.
Related Pathway
MAPK signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of FGF4 in NIH 3T3 cell lysate with FGF4 antibody at (A) 0.5 and (B) 1 ug/mL.
IF Image
Immunocytochemistry of FGF4 in 3T3 cells with FGF4 antibody at 2.5 ug/mL.

 

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