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Home Antibody All anti-CDNF antibodies

Anti-CDNF Antibody

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Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA306476 Rabbit Polyclonal CDNF Antibody 100ug $325 3-7 Days
LC422270 CDNF HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
IHC(1)
IF(1)
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Also for CDNF (NM_001029954)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenCDNF antibody was raised against a 9 amino acid peptide from near the carboxy terminus of human CDNF.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 2 - 4 ug/mL, ICC: 2.5 ug/mL, IF: 20 ug/mL
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target Namecerebral dopamine neurotrophic factor
Alternative NameARMETL1
Database LinkNP_001025125
Entrez Gene 441549 Human
Entrez Gene 227526 Mouse
Entrez Gene 361276 Rat
FunctionThe conserved dopamine neurotrophic factor (CDNF) is a neurotrophic factor for dopaminergic neurons and highly homologous to the mesencephalic-astrocyte-derived neuro-trophic factor. Somewhat surprisingly, CDCF is expressed at higher levels in tissues such as heart, skeletal muscle and testes than in brain. Similar to the glial cell line-derived neurotrophic factor (GDNF), CDNF can prevent the 6-hydroxylamine (6-OHDA)-induced degeneration of dopaminergic neurons in a rat model of Parkinson’s disease. Furthermore, CDNF was able to restore the dopaminergic function and prevent the degeneration of dopaminergic neurons in the substantia nigra, suggesting that CDNF might be suitable for the treatment of Parkinson’s disease. At least two isoforms of CDNF are known to exist. This antibody does not cross-react with MANF.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.


WB Image
Western blot analysis of CDNF in mouse brain tissue lysate with CDNF antibody at (A) 2 and (B) 4 ug/ml.
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IHC Image
Immunohistochemistry of CDNF in human brain tissue with CDNF antibody at 2.5 ug/ml.
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IF Image
Immunofluorescence of CDNF in Human Brain cells with CDNF antibody at 20 ug/mL.
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