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Home Antibody All anti-PLXDC1 antibodies

Anti-PLXDC1 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA306474 Rabbit Polyclonal TEM7 Antibody 100ug $325 3-7 Days
LC402784 PLXDC1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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Also for PLXDC1 (NM_020405)
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OriGene Data

ImmunogenTEM7 antibody was raised against a 16 amino acid peptide from near the carboxy terminus of human TEM7.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 0.5 - 2 ug/ml, IHC: 2.5 ug/ml, IF: 20 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens plexin domain containing 1 (PLXDC1)
Alternative NameTEM3; TEM7
Database LinkNP_065138
Entrez Gene 57125 Human
Entrez Gene 72324 Mouse
Entrez Gene 303505 Rat
FunctionTumor endothelial marker 7 (TEM7) was identified through serial analysis of gene expression on endothelial cells isolated from human normal and malignant colorectal tissues. Further experiments verified TEM7 was highly expressed in the endothelium of numerous other cancer types including breast, lung and brain tumors. At least four isoforms of TEM7 are known to exist; these include intracellular, secreted, and membrane-bound forms. A homologous protein, TEM7R (also known as PLXDC2), acts as a binding partner to TEM7 and is also abundantly expressed in the endothelium of malignant colorectal cancer but is absent or rare in normal colon mucosa. High expression of TEM7 is associated with metastasis and poor survival of patients with osteogenic sarcoma.
Related PathwaySecreted ProteinTransmembraneDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of TEM7 in human liver tissue lysate with TEM7 antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml.
Immunohistochemistry of TEM7 in mouse liver tissue with TEM7 antibody at 2.5 ug/ml.


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