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Home Antibody All anti-MORF4 antibodies

Anti-MORF4 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306449
  • Rabbit Polyclonal MORF4 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC416416) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
IHC(1)

OriGene Data

ImmunogenMORF4 antibody was raised against a 18 amino acid peptide from near the amino terminus of human MORF4.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens mortality factor 4 (MORF4)
Alternative NameCSR; CSRB; SEN; SEN1; CSRB; SEN; SEN1; senescence (cellular)-related 1; senescence-related, cellular, 1; mortality factor 4
Database LinkNP_006783
Entrez Gene 10934 Human
FunctionCellular senescence is the terminal non-dividing state that normal cells enter following completion of their proliferative potential. Fusions of immortal human cell lines with each other have led to their assignment to one of four complementation groups. Mortality factor 4 (MORF4) was identified as the lead member of a family of transcription factor-like proteins that reverses this immortal phenotype. Like other members in this family, MORF4 is localized to the nucleus and possesses transcription factor-like motifs such as helix-loop-helix and a leucine zipper motif that might allow it to form transcriptionally active homo- or heterodimers. MORF4 has been shown to bind to the transcription corepressors mSin3A and TLE, suggesting that together, these complexes may play a role in transcriptional repression of genes that lead to cellular senescence.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of MORF4 in K562 cell lysate with MORF4 antibody at (A) 1 and (B) 2 ug/ml.
IHC Image
Immunohistochemistry of MORF4 in human brain tissue with MORF4 antibody at 5 ug/ml.

 

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