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Home Antibody All anti-TRPC3 antibodies

Anti-TRPC3 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306352
  • Rabbit Polyclonal TRPC3 Antibody
100ug 325 In Stock
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WB(1)
IHC(1)

OriGene Data

ImmunogenTRPC3 antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human TRPC3.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 0.5 - 1 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens transient receptor potential cation channel, subfamily C, member 3 (TRPC3), transcript variant 1
Alternative NameTRP3
Database LinkNP_001124170
Entrez Gene 7222 Human
Entrez Gene 22065 Mouse
Entrez Gene 60395 Rat
FunctionThe mammalian transient receptor potential (TRP) superfamily can be divided into three major families including the “canonical TRP” (TRPC) family. The seven members of this family share the activation through PLC-coupled receptors and have been suggested to be components of receptor-regulated cation channels in different cell types. Furthermore, the members of the TRPC3/6/7 subfamily can be activated by diacylglycerol analogs, suggesting a possible mechanism of activation of these channels by PLC-coupled receptors. TRPC3 encodes a Ca2+-permeant channel that is agonist-activated but not store-operated or directly receptor-activated. TRPC3 physically interacts with TRPC6 and TRPC7 and forms functional tetrameric channels.
Related PathwayIon Channels: Transient receptor potentialTransmembraneDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of TRPC3 in human brain tissue lysate with TRPC3 antibody at (A) 1 and (B) 2 ug/ml.
IHC Image
Immunohistochemistry of TRPC3 in mouse heart tissue with TRPC3 antibody at 2 ug/ml.

 

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