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Home Antibody All anti-IL23A antibodies

Anti-IL23A Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA306314 Rabbit Polyclonal IL-23 Antibody 100ug $325 3-7 Days
LC402570 IL23A HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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Also for IL23A (NM_016584)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenIL-23 antibody was raised against a 16 amino acid peptide from near the carboxy terminus of human IL-23.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsWB: 1 ug/mL, ICC: 10 ug/mL, IF: 20 ug/mL
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens interleukin 23, alpha subunit p19 (IL23A)
Alternative NameIL-23; IL-23A; IL23P19; P19; SGRF
Database LinkNP_057668
Entrez Gene 51561 Human
Entrez Gene 83430 Mouse
FunctionLike interleukin-27 (IL-27), IL-23 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the IL-12p40 subunit and a novel p19 subunit. IL-23 is secreted by activated dendritic cells, macrophages, and monocytes. Its biological activities include enhancing the proliferation of memory T cells and the production of IFN-gamma, IL-12, and TNF-alpha from activated T cells, and can stimulate macrophages to produce TNF-alpha and nitric oxide. It has also been shown to possess potent anti-tumor and anti-metastatic activity in mouse models of cancer, suggesting a potential role for IL-23 in therapeutic treatment of cancer.
Related PathwaySecreted ProteinDruggable Genome Cytokine-cytokine receptor interactionJak-STAT signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of IL-23 in Raji lysate with IL-23 antibody at 1 ug/mL in the (A) absence and (B) presence of blocking peptide.

IF Image
Immunocytochemistry of IL-23 in Raji cells with IL-23 antibody at 10 ug/mL.

IF Image
Immunofluorescence of IL-23 in Raji cells with IL-23 antibody at 20 ug/mL.


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