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Home Antibody All anti-CASP7 antibodies

Anti-CASP7 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306202
  • Rabbit Polyclonal Caspase-7 Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC429055) , 20ug
100ug $325 3-7 Days
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WB(1)
IHC(1)
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Also for CASP7 (NM_001227)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenCaspase-7 antibody was raised against a 16 amino acid peptide from near the amino-terminus of human Caspase-7.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 0.5 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens caspase 7, apoptosis-related cysteine peptidase (CASP7), transcript variant a
Alternative NameCASP-7; CMH-1; ICE-LAP3; LICE2; MCH3
Database LinkNP_001218
FunctionCaspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens (reviewed in 1 and 2). The apoptotic subfamily can be further divided into initiator caspases, which are activated in response to death signals, and executioner caspases, which are activated by the initiator caspases and are responsible for cleavage of cellular substrates that ultimately lead to cell death (reviewed in 3). Caspase-7 is an executioner caspase that was identified based on its homology with caspases 1 and 3, as well as the C. elegans cell death protein CED-3 (4). Alternative splicing of Caspase-7 mRNA results in the production of 3 distinct isoforms (4). Caspase-7 activity can be directly inhibited by XIAP expression (5).
Related Pathway
Apoptosis
MAPK signaling pathway

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WB Image
Western blot analysis of Caspase-7 in mouse skeletal muscle cell lysate with Caspase-7 antibody at (A) 0.5 and (B) 1 ug/ml.
IHC Image
Immunohistochemistry of caspase-7 in rat skeletal muscle tissue with caspase-7 antibody at 10 ug/ml.

 

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