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Anti-BCL2L11 Antibody

* Buy one primary antibody, get 50% off a GAPDH loading control antibody.

WB(1)

IF(1)

OriGene Data

Immunogen	Bim antibody was raised against a peptide corresponding to amino acids near the center of human Bim The sequence is identical to that of mouse and rat.
Clone Name		Isotype	IgG
Species Reactivity	Human, Mouse, Rat	Concentration	1ug/ul
Guaranteed Application *	WB, IF	Suggested Dilutions	ELISA, WB: 2.5 - 5 ug/ml, ICC: 10 ug/ml, IF: 20 ug/ml
Buffer	PBS containing 0.02% sodium azide.
Purification	Affinity chromatography purified via peptide column (Protein A or G Sepharose)

Reference Data

Target Name	Homo sapiens BCL2-like 11 (apoptosis facilitator) (BCL2L11), transcript variant 6
Alternative Name	BAM; BIM; BOD
Database Link	NP_006529
Function	Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. A novel BH3 domain containing protein was recently identified and designated Bim or BOD in human, mouse and rat (1,2). Bim/BOD interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, Bcl-xL and Bcl-w. Bim/BOD induces apoptosis. The messenger RNA of Bim is ubiquitously expressed in multiple tissues and cell lines (1,2).
Related Pathway	Apoptosis

Related Lysate from OriGene • Transient overexpression lysate of BCL2-like 11 (apoptosis facilitator) (BCL2L11), transcript variant 6 Anti-Tag Antibodies & WB Reagent • Anti-Tag Antibodies • Western Blot Reagent shRNA • BCL2L11 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector • BCL2L11 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector • Bcl2l11 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector • BCL2L11 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector • Bcl2l11 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector Related ORF Clones • Myc-DDK-tagged ORF clone of Homo sapiens BCL2-like 11 (apoptosis facilitator) (BCL2L11), transcript variant 6 as transfection-ready DNA • Lenti ORF clone of Human BCL2-like 11 (apoptosis facilitator) (BCL2L11), transcript variant 6, mGFP tagged • GFP-tagged ORF clone of Homo sapiens BCL2-like 11 (apoptosis facilitator) (BCL2L11), transcript variant 6 as transfection-ready DNA • Lenti ORF clone of Human BCL2-like 11 (apoptosis facilitator) (BCL2L11), transcript variant 6 , Myc-DDK-tagged Related cDNA Clones • ORIGENE UNIQUE VARIANT 1 of Homo sapiens BCL2-like 11 (apoptosis facilitator) (BCL2L11), as transfection-ready DNA • Homo sapiens BCL2-like 11 (apoptosis facilitator) (BCL2L11), transcript variant 6 as transfection-ready DNA

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

• HRP
• Biotin
• PE
• FITC
• DyLight® 488
• DyLight® 550
• DyLight® 594
• DyLight® 633

* DyLight is a trademark of Thermo-Fisher Scientific

Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)