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Home Antibody All anti-BID antibodies

Anti-BID Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306178
  • Rabbit Polyclonal Bid Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC420074) , 20ug
100ug 325 3-7 Days
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WB(1)
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Also for BID (NM_001196)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenBid antibody was raised against a peptide corresponding to 14 amino acids near the middle of human Bid.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration1ug/ul
Guaranteed Application *WB Suggested DilutionsWB: 1 - 2 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Ion exchange chromatography purified

Reference Data

Target NameHomo sapiens BH3 interacting domain death agonist (BID), transcript variant 2
Alternative NameFP497
Database LinkNP_001187
FunctionApoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer (reviewed in 1). The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death (reviewed in 2 and 3). Bid, a pro-apoptotic Bcl-2 family member, is cleaved by caspase-8 in response to apoptotic signals (4,5), exposing the Bcl-2 homology 3 (BH3) domain which is normally buried in the full-length protein (6). The cleaved complex is myris-toylated and translocated to the mitochondrial membrane where it may induce mitochondrial Bax and Bak to oligomerize (7,8).
Related Pathway
Apoptosis

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of Bid in A549 cell lysates with Bid antibody at (A) 0.5, (B) 1, and (C) 2 µg/ml.

 

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