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Home Antibody All anti-NAIP antibodies

Anti-NAIP Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA306166 Rabbit Polyclonal NAIP Antibody 100ug $325 3-7 Days
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OriGene Data

ImmunogenNAIP antibody was raised against a synthetic peptide corresponding to 13 amino acids at the C-terminus of human NAIP.
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsWB: 0.5 - 2 ug/mL, ICC: 10 ug/mL, IF: 20 ug/mL
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens NLR family, apoptosis inhibitory protein (NAIP), transcript variant 1
Alternative NameBIRC1; NLRB1; psiNAIP
Database LinkNP_004527
Entrez Gene 4671 Human
FunctionNeuronal apoptosis inhibitor protein (NAIP) was the first human inhibitor of apoptosis protein (IAP) identified and was discovered by its association with the neurodegenerative disorder spinal muscular atrophy (1,2). Members of the IAP family contain one to three copies of an approximately 70 amino acid motif termed baculovirus IAP repeat (BIR); these BIRs promote protein-protein interactions with various caspases such as caspase-3, -7, and -9 as well as members of the TRAF family of signal molecules (reviewed in 3). Unlike other IAPs however, NAIP requires ATP to bind caspase-9 and is not inhibited by the IAP-inhibiting molecule Smac/DIABLO (4), suggesting that NAIP is unique among the IAPs in its regulation of its activity. Finally, although only one human NAIP protein has been identified, other shorter NAIP mRNA transcripts have been reported (5).
Related PathwayDruggable Genome NOD-like receptor signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of NAIP in PC-3 cell lysate with NAIP antibody at (A) 0.5, (B) 1, and (C) 2 ug/mL.

IF Image
Immunocytochemistry of NAIP in A549 cells with NAIP antibody at 10 ug/mL.

IF Image
Immunofluorescence of NAIP in A549 cells with NAIP antibody at 20 ug/mL.


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