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Home Antibody All anti-NAIP antibodies

Anti-NAIP Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306166
  • Rabbit Polyclonal NAIP Antibody
100ug $325 3-7 Days
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WB(1)
IF(1)

OriGene Data

ImmunogenNAIP antibody was raised against a synthetic peptide corresponding to 13 amino acids at the C-terminus of human NAIP.
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsELISA, WB: 0.5 - 2 ug/ml, ICC: 10 ug/ml, IF: 20 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens NLR family, apoptosis inhibitory protein (NAIP), transcript variant 1
Alternative NameBIRC1; NLRB1; psiNAIP
Database LinkNP_004527
FunctionNeuronal apoptosis inhibitor protein (NAIP) was the first human inhibitor of apoptosis protein (IAP) identified and was discovered by its association with the neurodegenerative disorder spinal muscular atrophy (1,2). Members of the IAP family contain one to three copies of an approximately 70 amino acid motif termed baculovirus IAP repeat (BIR); these BIRs promote protein-protein interactions with various caspases such as caspase-3, -7, and -9 as well as members of the TRAF family of signal molecules (reviewed in 3). Unlike other IAPs however, NAIP requires ATP to bind caspase-9 and is not inhibited by the IAP-inhibiting molecule Smac/DIABLO (4), suggesting that NAIP is unique among the IAPs in its regulation of its activity. Finally, although only one human NAIP protein has been identified, other shorter NAIP mRNA transcripts have been reported (5).
Related Pathway

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WB Image
Western blot analysis of NAIP in PC-3 cell lysate with NAIP antibody at (A) 0.5, (B) 1, and (C) 2 ug/mL.
IF Image
Immunocytochemistry of NAIP in A549 cells with NAIP antibody at 10 ug/mL.

 

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