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Home Antibody All anti-BCL2L14 antibodies

Anti-BCL2L14 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306135
  • Rabbit Polyclonal Bcl-G Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC429763) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
IHC(1)
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Also for BCL2L14 (NM_030766)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenBcl-G antibody was raised against a peptide corresponding to 15 amino acids near the C-terminus of human Bcl-G.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 2.5 - 5 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Ion exchange chromatography purified

Reference Data

Target NameHomo sapiens BCL2-like 14 (apoptosis facilitator) (BCL2L14), transcript variant 2
Alternative NameBCLG
Database LinkNP_110393
Entrez Gene 79370 Human
Entrez Gene 66813 Mouse
Entrez Gene 500348 Rat
FunctionMembers in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain (reviewed in 1 and 2). BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. A novel BH3 domain containing protein was recently identified and designated Bcl-G (3). The mRNA of Bcl-G encodes 2 isoforms, Bcl-GL, which is widely expressed in multiple tissues, and Bcl-GS, which is only found in testis. The Bcl-GS protein is predominantly localized to cytoplasmic organelles whereas Bcl-GL was distributed throughout the cytosol. Overexpression of either protein induced apoptosis, although Bcl-GS was far more potent than Bcl-GS. Apoptosis induction was dependent on the BH3 domain and could be suppressed by co-expression with the anti-apoptotic Bcl-XL protein (3)..
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of Bcl-G in U937 cell lysates with Bcl-G antibody at (A) 2.5 and (B) 5 ug/ml.
IHC Image
Immunohistochemical staining of mouse testis tissue using Bcl-G antibody at 2 ug/ml.

 

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