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Home Antibody All anti-BCL2L10 antibodies

Anti-BCL2L10 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306134
  • Rabbit Polyclonal Bcl-B Antibody
100ug 325 3-7 Days
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WB(1)
IF(1)

OriGene Data

ImmunogenBcl-B antibody was raised against a 16 amino acid peptide from near the amino terminus of human Bcl-B.
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsELISA, WB: 1 ug/ml, ICC: 10 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens BCL2-like 10 (apoptosis facilitator) (BCL2L10)
Alternative NameBCL-B; Boo; Diva
Database LinkNP_065129
FunctionMembers in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-B is a recently discovered anti-apoptotic member of the Bcl-2. Unlike the mouse homolog (also known as Diva/Boo) which is predominantly expressed in ovary and testis, the human Bcl-B protein is widely expressed. Also, the human Bcl-B functions by binding to and suppressing the apoptotic activity of Bax, whereas the mouse homolog binds Bak and also interacts with the apoptosis protein Apaf-1. Despite its predicted molecular weight, Bcl-B is often at higher molecular weights, presumably due to post-translational modifications.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of Bcl-B in Jurkat lysate with Bcl-B antibody at 1 ug/ml in the (A) absence and (B) presence of blocking peptide.
IF Image
Immunocytochemistry of Bcl-B in Jurkat cells with Bcl-B antibody at 10 ug/mL.

 

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