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Home Antibody All anti-PAK6 antibodies

Anti-PAK6 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA306114 Rabbit Polyclonal PAK6 Antibody 100ug $325 3-7 Days
LC426985 PAK6 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenPAK6 antibody was raised against a 13 amino acid peptide from near the center of human PAK6.
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsWB: 1 - 4 ug/mL, ICC: 10 ug/mL, IF: 10 ug/mL
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens p21 protein (Cdc42/Rac)-activated kinase 6 (PAK6), transcript variant 2
Alternative NamePAK5
Database LinkNP_001122100
Entrez Gene 56924 Human
FunctionThe p21-activated kinases (PAKs) are serine-threonine kinases that bind to the active forms of Cdc42 and Rac. They are divided into two groups, the first of which include PAK1, 2 and 3, and can be activated by Cdc42/Rac binding. Group 1 PAKs contain an autoinhibitory domain whose activity is regulated by Cdc42/Rac binding. The group 1 PAKs are known to be involved in cellular processes such as gene transcription, apoptosis, and cell morphology and motility. Much less is known about the second group, which includes PAK4, 5 and 6. These proteins are not activated by Cdc42/Rac binding. PAK6 was initially identified as an androgen receptor in a yeast two hybrid screen and was found to be highly expressed in testis and prostate tissues. Later experiments have shown it to be activated by MAP kinase kinase 6 and p38 MAP kinase, suggesting that PAK6 may play a role in the cellular response to stress-related signals.
Related PathwayProtein KinaseDruggable Genome ErbB signaling pathwayAxon guidanceFocal adhesionT cell receptor signaling pathwayRegulation of actin cytoskeletonRenal cell carcinomaMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of PAK6 in Raji lysate with PAK6 antibody at (A) 1, (B) 2, and (C) 4 ug/mL.

IF Image
Immunocytochemistry of PAK6 in Raji cells with PAK6 antibody at 10 ug/mL.

IF Image
Immunofluorescence of PAK6 in Raji cells with PAK6 antibody at 10 ug/mL.


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