Home Antibody All anti-KLHL1 antibodies
Also for KLHL1 (NM_020866)
|KLHL1 antibody was raised against a 14 amino acid peptide from near the amino-terminus of human KLHL1.|
||WB: 2-4ug/ml; IHC: 10ug/ml
|PBS containing 0.02% sodium azide.|
|immunoaffinity purified (Protein A or G Sepharose)
|Homo sapiens kelch-like family member 1 (KLHL1), transcript variant 1|
|The mammalian Kelch-like 1 (KLHL1) was initially discovered as a homolog to the Drosophila Kelch gene that is highly expressed in several brain tissues (1,2). The predicted protein domain structure of KLHL1 is characteristic of a number of proteins that bind actin, form dimers, and often act as actin-organizing proteins (3). Based on the presence of anti-sense RNA that spans the transcription and translation start sites as well as the first splice site of KLHL1 in brain tissue of individuals suffering from the neurodegenerative disorder spinocerebellar ataxia type 8 (SCA8), it has been suggested that KLHL1 is involved this disease and that regulation of KLHL1 protein may be affected by antisense RNA expression (1).|
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Western blot analysis of KLHL1 in human brain cell lysate with KLHL1 antibody at (A) 2 and (B) 4 ug /ml.
Immunohistochemistry of KLHL1 in rat brain tissue with KLHL1 antibody at 10 ug/ml.