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Home Antibody All anti-KLHL1 antibodies

Anti-KLHL1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306098
  • Rabbit Polyclonal KLHL1 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC412235) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
IHC(1)

OriGene Data

ImmunogenKLHL1 antibody was raised against a 14 amino acid peptide from near the amino-terminus of human KLHL1.
Clone Name IsotypeIgG
Species ReactivityHuman, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 2-4ug/ml; IHC: 10ug/ml
BufferPBS containing 0.02% sodium azide.
Purification immunoaffinity purified

Reference Data

Target NameHomo sapiens kelch-like family member 1 (KLHL1), transcript variant 1
Alternative NameMRP2
Database LinkNP_065917
Entrez Gene 57626 Human
Entrez Gene 290426 Rat
FunctionThe mammalian Kelch-like 1 (KLHL1) was initially discovered as a homolog to the Drosophila Kelch gene that is highly expressed in several brain tissues (1,2). The predicted protein domain structure of KLHL1 is characteristic of a number of proteins that bind actin, form dimers, and often act as actin-organizing proteins (3). Based on the presence of anti-sense RNA that spans the transcription and translation start sites as well as the first splice site of KLHL1 in brain tissue of individuals suffering from the neurodegenerative disorder spinocerebellar ataxia type 8 (SCA8), it has been suggested that KLHL1 is involved this disease and that regulation of KLHL1 protein may be affected by antisense RNA expression (1).
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of KLHL1 in human brain cell lysate with KLHL1 antibody at (A) 2 and (B) 4 ug /ml.
IHC Image
Immunohistochemistry of KLHL1 in rat brain tissue with KLHL1 antibody at 10 ug/ml.

 

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