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Home Antibody All anti-TRAF3IP2 antibodies

Anti-TRAF3IP2 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306088
  • Rabbit Polyclonal CIKS Antibody
100ug 325 3-7 Days
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WB(1)
IHC(1)
IF(1)
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Also for TRAF3IP2 (NM_001164281)
cDNA Clone shRNA/siRNA Primer Pair Protein Request Antibody

OriGene Data

ImmunogenCIKS antibody was raised against a synthetic peptide corresponding to amino acids 2 to 15 of human CIKS .
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1ug/ul
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 ug/ml, IHC: 5 ug/ml, IF: 20 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens TRAF3 interacting protein 2 (TRAF3IP2), transcript variant 3
Alternative NameACT1; C6orf2; C6orf4; C6orf5; C6orf6; CANDF8; CIKS; PSORS13
Database LinkNP_001157753
FunctionNuclear factor kappa B (NF-kappaB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kappaB mediates the expression of a great variety of genes in response to extracellular stimuli. NF-kappaB associates with IkappaB proteins in the cell cytoplasm, which inhibit NF-kappaB activity. IkappaB is phosphorylated by IkappaB kinase (IKK) complex that contains IKKalpha, IKKbeta, and IKKgamma. A novel molecule that associates with and activates IKK was recently identified and designated CIKS (for connection to IKK and SAPK/JNK) and Act1 (for NF-kappaB activator 1) (1,2). CIKS directly interacts with IKKgamma. CIKS/Act1 also activates activating transcription factor (ATF) and activator protein 1 (AP-1) through Jun kinase (JNK). These results indicate that CIKS/Act1 is involved in the inflammation and stress responses. CIKS/Act1 is ubiquitously expressed in human tissues.
Related Pathway

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WB Image
Western blot analysis of CIKS expression in human lung (lane A) and placenta (lane B) tissue lysates with CIKS antibody at 1 ug /ml.
IHC Image
Immunohistochemistry of CIKS in human lung tissue with CIKS antibody at 5 ug/ml.
IF Image
Immunofluorescence of CIKS in human lung tissue with CIKS antibody at 20 ug/mL.

 

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