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Home Antibody All anti-TNFSF13 antibodies

Anti-TNFSF13 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306069
  • Rabbit Polyclonal APRIL Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401250) , 20ug
100ug 325 3-7 Days
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WB(1)
IHC(1)
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Also for TNFSF13 (NM_003808)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenAPRIL antibody was raised against a synthetic peptide corresponding to amino acids within a extracellular domain of human APRIL.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1 - 4 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens tumor necrosis factor (ligand) superfamily, member 13 (TNFSF13), transcript variant alpha
Alternative NameAPRIL; CD256; TALL-2; TALL2; TRDL-1; UNQ383/PRO715; ZTNF2
Database LinkNP_003799
FunctionMembers in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated APRIL (for a proliferation-inducing ligand), TALL-2 (for TNF- and ApoL-related Leukocyte-expressed Ligand 2), and TRDL-1a (for TNF related death ligand 1a) in human and mouse (1-4). Two receptors for APRIL were recently identified and designated TACI and BCMA (5-7). APRIL stimulates B and T cell proliferation, triggers humoral immune responses, activates NF-kappaB, and induces cell death (1-7). APRIL and its close relative of BlyS and their receptors BCMA and TACI are involved in diseases of autoimmunity and cancer (8,9).
Related Pathway
Cytokine-cytokine receptor interaction

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WB Image
Western blot analysis of APRIL expression in Jurkat cells with APRIL antibody at 1 ug/ml (A), 2 ug/ml (B), and 4 ug/ml (C).
IHC Image
Immunohistochemistry of APRIL in human prostate tissue with APRIL antibody at 10 ug/ml.

 

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