OriGene Technologies, Inc.
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-TNFRSF17 antibodies

Anti-TNFRSF17 Antibody

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306065
  • Rabbit Polyclonal BCMA Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400483) , 20ug
100ug $325 In Stock
Add to Shopping Cart
WB(1)
IHC(1)
spacer
Also for TNFRSF17 (NM_001192)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenBCMA antibody was raised against a synthetic peptide mapping at the carboxy terminus of human BCMA .
Clone Name IsotypeIgG
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC Suggested DilutionsWB: 2 - 5 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens tumor necrosis factor receptor superfamily, member 17 (TNFRSF17)
Alternative NameBCM; BCMA; CD269; TNFRSF13A
Database LinkNP_001183
FunctionMembers in the TNF superfamily regulate immune responses and induce apoptosis. Two novel members in the TNF family were recently identified and designated BAFF/BLyS/TALL-1/THANK/zTNF4 (1-4) and April/TALL-2, respectively, (3,5). BAFF was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion (1,2). April regulates immunological and non-immunological cell growth. Three receptors, BCMA (for B cell maturation protein), TACI, and BAFF-R, for BAFF were recently identified (6,7). BCMA, like TACI, binds BAFF and April. BAFF and its receptors induce B cell development and survival, activate NF-kB and c-jun N-terminal kinase, and are involved in B cell associated autoimmune diseases.
Related Pathway
Cytokine-cytokine receptor interaction

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of BCMA in human spleen (A) tissue lysate, K562 (B), and U937 (C) cell lysates with BCMA antibody at 5 ug/ml.
IHC Image
Immunohistochemistry of BCMA in human spleen cells with BCMA antibody at 10 ug/ml.

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title