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Home Antibody All anti-TNFRSF13B antibodies

Anti-TNFRSF13B Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306064
  • Rabbit Polyclonal TACI Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC402216) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
IF(1)
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Also for TNFRSF13B (NM_012452)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenTACI antibody was raised against a synthetic peptide mapping at the amino terminus of human TACI .
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsELISA, WB: 5 ug/ml, ICC: 2 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens tumor necrosis factor receptor superfamily, member 13B (TNFRSF13B)
Alternative NameCD267; CVID; CVID2; RYZN; TACI; TNFRSF14B
Database LinkNP_036584
Entrez Gene 23495 Human
FunctionMembers in the TNF superfamily regulate immune responses and induce apoptosis. Two novel members in the TNF family were recently identified and designated BAFF/BLyS/TALL-1/THANK/zTNF4 (1-4) and April/TALL-2, respectively, (3,5). BAFF was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion (1,2). April regulates immunological and non-immunological cell growth. Three receptors, BCMA, TACI, and BAFF-R, for BAFF and April were recently identified (6,7). TACI, like BCMA, binds BAFF and April. TACI and its ligands regulate humoral immune responses, activate NF-kappaB and c-jun N-terminal kinase, and are involved in B cell associated autoimmune diseases.
Related PathwayTransmembraneDruggable Genome Cytokine-cytokine receptor interactionPrimary immunodeficiency

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of TACI in K562 (A) and U937 (B) cell lysates with TACI antibody at 5 ug/mL.
IF Image
Immunocytochemistry of TACI in K562 cells with TACI antibody at 2 ug/mL.

 

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