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Home Antibody All anti-CD209 antibodies

Anti-CD209 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306058
  • Rabbit Polyclonal DC-SIGN Antibody
100ug $325 3-7 Days
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WB(1)
IHC(1)

OriGene Data

ImmunogenDC-SIGN antibody was raised against a synthetic peptide corresponding to amino acids near the center of human DC-DIGN .
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1 - 2 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens CD209 molecule (CD209), transcript variant 5
Alternative NameCDSIGN; CLEC4L; DC-SIGN; DC-SIGN1
Database LinkNP_001138365
FunctionDendritic cells (DCs) that control immune responses were recently found to capture and transport HIV from the mucosal area to remote lymph nodes (1), where DCs hand over HIV to CD4+ T lymphocytes. DCs also amplify the amount of virus and extend the duration of viral infectivity. Multiple strains of HIV-1, HIV-2 and SIV bind to DCs via DC-SIGN (2). ICAM-3 is the natural ligand for DC-SIGN (3). A DC-SIGN homologue (termed DC-SIGNR, L-SIGN, and DC-SIGN2) was identified recently (4-8). DC-SIGN forms a novel gene family with DC-SIGNR and many alternatively spliced isoforms of DC-SIGN and DC-SIGNR (8). The expression of DC-SIGN was found in mucosal tissues including placenta, small intestine, and rectum.
Related Pathway

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WB Image
Western blot detection of DC-SIGN in human small intestine at (A) 1 and (B) 2 ug /ml.
IHC Image
Immunohistochemistry of DC-SIGN in human lymph node tissue with DC-SIGN antibody at 10 ug/ml.

 

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