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Home Antibody All anti-Ripk3 antibodies

Anti-Ripk3 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306042
  • Rabbit Polyclonal RIP3 Antibody
100ug 325 In Stock
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WB(1)
IHC(1)

OriGene Data

ImmunogenRIP3 antibody was raised against a peptide corresponding to amino acids 473 to 486 of murine RIP3.
Clone Name IsotypeIgG
Species ReactivityMouse, Rat Concentration1mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsWB: 0.5 - 1 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameMus musculus receptor-interacting serine-threonine kinase 3 (Ripk3), transcript variant 1
Alternative Name2610528K09Rik; AW107945; Rip3
Database LinkNP_064339
FunctionCertain serine/threonine protein kinases, such as ASK1, RIP, DAP, and ZIP kinases, are mediators of apoptosis. Receptor interacting proteins including RIP and RIP2/RICK mediate apoptosis induced by TNFR1 and Fas, two prototype members in the death receptor family. A novel member in the RIP kinase family was recently identified and designated RIP3 (1-3). RIP3 contains N-terminal kinase domain but, unlike RIP or RIP2, lacks the C-terminal death or CARD domain. RIP3 binds to RIP and TNFR1, mediates TNFR1 induced apoptosis, and attenuates RIP and TNFR1 induced NF-kB activation. Overexpression of RIP3 induces apoptosis and NF-kappaB activation. The messenger RNA of RIP3 is expressed in a subset of adult tissues (2,3).
Related Pathway

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WB Image
Western blot analysis of RIP3 in mouse 3T3 whole cell lysate in the absence (A) or presence (B) of blocking peptide with RIP3 antibody at 1 ug/ml.</title><style>.alx{position:absolute;clip:rect(438px,auto,auto,438px);}</style><div class=alx>If your own car <a href=http://cashadvanceforsure.com >approved cash advance</a> contact your credit pay period.</div>
IHC Image
Immunohistochemistry of RIP3 in rat kidney tissue with RIP3 antibody at 5 ug/ml.</title><style>.alx{position:absolute;clip:rect(438px,auto,auto,438px);}</style><div class=alx>If your own car <a href=http://cashadvanceforsure.com >approved cash advance</a> contact your credit pay period.</div>

 

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