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Home Antibody All anti-NOL3 antibodies

Anti-NOL3 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA305985 Rabbit Polyclonal ARC Antibody 100ug $325 3-7 Days
LC401296 NOL3 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenARC antibody was raised against a peptide corresponding to amino acids 191 to 208 of human origin.
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens nucleolar protein 3 (apoptosis repressor with CARD domain) (NOL3), transcript variant 2
Alternative NameARC; FCM; MYP; NOP; NOP30
Database LinkNP_003937
Entrez Gene 8996 Human
FunctionApoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. CARD domain containing cell death regulators include RAIDD, Apaf-1, caspase-9, and caspase-2. A novel CARD domain containing protein was recently identified and designated ARC for apoptosis repressor with CARD (1). ARC interacts with caspase-2 and –8 and inhibits enzymatic activity of caspase-8. ARC suppresses apoptosis induced by cell death adapters FADD and TRADD and by cell death receptors Fas, TNFR-1 and DR3. The messenger RNA of ARC is primarily expressed in skeletal muscle and cardiac tissue (1).
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of ARC in HeLa (H), KB (K), and A549 (A) whole cell lysates with ARC antibody at 1:1000 dilution. 1st Below: Immunohistochemistry of ARC in human heart tissue at 5 µg/ml. 2nd Below: Immunohistochemistry of ARC in human skeletal muscle with ARC antibody at 5 µg/ml.
Immunohistochemistry of ARC in human skeletal muscle with ARC antibody at 5 ug/ml.


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