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Home Antibody All anti-DAPK3 antibodies

Anti-DAPK3 Antibody

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Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA305981 Rabbit Polyclonal ZIPK Antibody 100ug $325 In Stock
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WB(1)
IF(2)
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Also for DAPK3 (NM_001348)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenZIP kinase antibody was raised against a peptide corresponding to amino acids near the center of human ZIP kinase.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1mg/ml
Guaranteed Application *WB, IF Suggested DilutionsWB: 1 ug/mL, ICC: 10 ug/mL, IF: 10 ug/mL
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target Namedeath associated protein kinase 3
Alternative NameDLK|ZIP|ZIPK
Database LinkNP_001339
Entrez Gene 1613 Human
Entrez Gene 13144 Mouse
Entrez Gene 64391 Rat
FunctionApoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as ASK-1 and RIP, are mediators of apoptosis. A novel serine/threonine kinase that mediates apoptosis was recently identified and designated ZIP kinase . ZIP kinase contains an N-terminal kinase domain and a C-terminal leucine zipper structure and binds to ATF4 that is a member of ATF/CREB family. ZIP kinase has high sequence homology to DAP kinase (death-associated protein kinase), which is a mediator of apoptosis induced by gamma interferon. Overexpression of ZIP kinase induces apoptosis. ZIP and DAP kinases represent a novel kinase family, which mediates apoptosis through their catalytic activities. The messenger RNA was ubiquitously expressed in various tissues .
Related PathwayProtein KinaseDruggable Genome Pathways in cancerBladder cancer

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.


WB Image
Western blot analysis of ZIP kinase in HeLa (H) and Jurkat (J) whole cell lysates with ZIP kinase antibody at 1 ug/mL.
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IF Image
Immunocytochemistry of ZIP kinase in Jurkat cells with ZIP kinase antibody at 10 ug/mL.
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IF Image
Immunofluorescence of ZIPK in Jurkat cells with ZIPK antibody at 10 ug/mL.
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