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Home Antibody All anti-TLN1 antibodies

Anti-TLN1 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA305932 Goat Anti-Talin 1 / TLN1 Antibody 100ug $325 3-7 Days
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WB(1)

OriGene Data

ImmunogenPeptide with sequence C-QEALHTQMLTAVQE, from the internal region of the protein sequence according to NP_006280.3.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human. Expected from seq similarity: Human, Mouse, Rat, Dog, Cow Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 0.03-0.1ug/ml.
Buffer0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing.

Reference Data

Target NameHomo sapiens talin 1 (TLN1)
Alternative NameILWEQ; TLN
Database LinkNP_006280
Entrez Gene 7094 Human
Entrez Gene 21894 Mouse
Entrez Gene 313494 Rat
Entrez Gene 100856393 Dog
FunctionThis gene encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. The encoded protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin. [provided by RefSeq].
Related PathwayDruggable Genome Focal adhesion

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

TA305932 (1ug/ml) staining of Human Peripheral Mononucleocytes lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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