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Home Antibody All anti-Actl7b antibodies

Anti-Actl7b Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA305837
  • Goat Anti-Actin-like 7B (mouse) Antibody
100ug 325 3-7 Days
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WB(1)

OriGene Data

ImmunogenPeptide with sequence C-DELHVDYELPDGK, from the internal region of the protein sequence according to NP_079547.1.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Rat. Expected from seq similarity: Mouse, Rat Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 0.03-0.1ug/ml.
Buffer0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing.

Reference Data

Target NameMus musculus actin-like 7b (Actl7b)
Alternative NameTact1
Database LinkNP_079547
Entrez Gene 11471 Mouse
Entrez Gene 313183 Rat
FunctionAtrophin-1 contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian atrophy. The protein encoded by this gene interacts with atrophin-1. This encoded protein is a closely related member of the NEDD4-like protein family. This family of proteins are E3 ubiquitin-ligase molecules and regulate key trafficking decisions, including targeting of proteins to proteosomes or lysosomes. This encoded protein contains four tandem WW domains and a HECT (homologous to the E6-associated protein carboxyl terminus) domain. It can act as a transcriptional corepressor of p45/NFE2 and may participate in the regulation of immune responses by modifying Notch-mediated signaling. It is highly similar to the mouse Itch protein, which has been implicated in the regulation and differentiation of erythroid and lymphoid cells. [provided by RefSeq].
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
TA305837 (0.5ug/ml) staining of Rat Testes lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

 

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