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Home Antibody All anti-IMPDH2 antibodies

Anti-IMPDH2 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA305796
  • Goat Anti-IMPDH2 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC424469) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
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Also for IMPDH2 (NM_000884)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenPeptide with sequence KEEEHDCFLEEI, from the internal region of the protein sequence according to NP_000875.2.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human. Expected from seq similarity: Human Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 1-3ug/ml.
Buffer0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing.

Reference Data

Target NameHomo sapiens IMP (inosine 5'-monophosphate) dehydrogenase 2 (IMPDH2)
Alternative NameIMPD2; IMPDH-II
Database LinkNP_000875
Entrez Gene 3615 Human
FunctionThis gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. [provided by RefSeq].
Related PathwayDruggable Genome Purine metabolismDrug metabolism - other enzymesMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
TA305796 (1ug/ml) staining of Human Skeletal Muscle lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

 

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