Home Antibody All anti-FMR1 antibodies
Also for FMR1 (NM_002024)
|Peptide with sequence C-RTGKDRNQKKEKPD, from the internal region (near the C Terminus) of the protein sequence according to NP_002015.1.|
|Test: Human. Expected from seq similarity: Human, Mouse, Rat, Dog
|0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing.
|Homo sapiens fragile X mental retardation 1 (FMR1), transcript variant ISO1|
|FMRP; FRAXA; POF; POF1; POFX|
Entrez Gene 2332 Human
Entrez Gene 14265 Mouse
Entrez Gene 24948 Rat
Entrez Gene 481070 Dog
|The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). [provided by RefSeq]. |
|Druggable Genome |
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TA305782 (0.1ug/ml) staining of KELLY cell lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.