Home Antibody All anti-PPP2R4 antibodies
Also for PPP2R4 (NM_021131)
|Peptide with sequence C-GSLLPIHPVTSG, from the C-Terminus of the protein sequence according to NP_821068.1; NP_066954.2; NP_821070.1.|
|Test: Human, Mouse, Rat. Expected from seq similarity: Human, Mouse, Rat, Dog, Cow
|0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing.
|Homo sapiens protein phosphatase 2A activator, regulatory subunit 4 (PPP2R4), transcript variant 3|
|PP2A; PR53; PTPA|
Entrez Gene 5524 Human
Entrez Gene 110854 Mouse
Entrez Gene 362102 Rat
Entrez Gene 491303 Dog
|Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]. |
|PhosphataseDruggable Genome |
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TA305706 (0.5ug/ml) staining of Human Liver lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.