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Home Antibody All anti-FLNA antibodies

Anti-FLNA PHOSPHO Antibody EP2309Y

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SKU Description Amount Price Availability*  
TA303836
  • Rabbit monoclonal antibody against Filamin A Phospho (pS1458) (EP2309Y ) (phospho-specific)
100ul $325 In Stock
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WB(1)
IHC(1)

OriGene Data

ImmunogenA phospho specific peptide corresponding to residues surrounding serine 1458 of human Filamin A was used as an immunogen. This antibody detects Filamin A phosphorylated at serine 1458.
Clone NameEP2309Y IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:5000; IHC-P: 1:50 - 1:100; ICC/IF: 1:50 - 1:100
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt or IP.

Reference Data

Target NameHomo sapiens filamin A, alpha (FLNA), transcript variant 1
Alternative NameABP-280; ABPX; CSBS; CVD1; FLN; FLN-A; FLN1; FMD; MNS; NHBP; OPD; OPD1; OPD2; XLVD; XMVD
Database LinkNP_001447
Entrez Gene 2316 Human
FunctionActin-binding protein, or filamin, is a 280-kD protein that crosslinks actin filaments into orthogonal networks in cortical cytoplasm and participates in the anchoring of membrane proteins for the actin cytoskeleton. Remodeling of the cytoskeleton is central to the modulation of cell shape and migration. Filamin A, encoded by the FLNA gene, is a widely expressed protein that regulates reorganization of the actin cytoskeleton by interacting with integrins, transmembrane receptor complexes, and second messengers.[supplied by OMIM].
Related Pathway MAPK signaling pathwayFocal adhesion

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Filamin A (phospho S1458) antibody [EP2309Y]; All lanes : Anti-Filamin A (phospho S1458) antibody [EP2309Y] at 1/5000 dilution.Lane 1 : HeLa cell lysate - untreated.Lane 2 : HeLa cell lysate - treated with AP.Lysates/proteins at 10 ug per lane.Secondary.HRP-labelled Goat anti-Rabbit antibody at 1/2000 dilution.Predicted band size : 280 kDa.Observed band size : 260 kDa .
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Filamin A (phospho S1458) antibody [EP2309Y]; Immunohistochemical analysis of paraffin-embedded human stomach (left) and human uterus tissue (right) using 1/50 TA303836. Heat-mediated antigen retrieval was performed prior to commencing with IHC protocol and an HRP-conjugated polymerized secondary antibody was used.
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