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Home Antibody All anti-PDK1 antibodies

Anti-PDK1 PHOSPHO Antibody EP569Y

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303835
  • Rabbit monoclonal antibody against Phospho PDPK1 (pY373/376)(EP569Y) (phospho-specific)
100ul 325 3-7 Days
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WB(1)
IHC(1)
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Also for PDK1 (NM_002610)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenSynthetic phospho-peptide corresponding to residues surrounding Tyr373 and Tyr376 of human PDPK1.
Clone NameEP569Y IsotypeIgG
Species ReactivityMouse, Rat, Human, Pig ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000; IHC-P: Use at an assay dependent dilution
Predicted MW Explanation 63 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,ICC/IF or IP.

Reference Data

Target NameHomo sapiens pyruvate dehydrogenase kinase, isozyme 1 (PDK1), transcript variant 2
Alternative Namemitochondrial pyruvate dehydrogenase kinase isoenzyme 1; pyruvate dehydrogenase kinase, isoenzyme 1; pyruvate dehydrogenase kinase, isozyme 1
Database LinkNP_002601
Entrez Gene 5163 Human
Entrez Gene 228026 Mouse
Entrez Gene 116551 Rat
FunctionPyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. [provided by RefSeq].
Related PathwayProtein KinaseDruggable Genome T cell receptor signaling pathwayFc epsilon RI signaling pathwayNeurotrophin signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - PDPK1 antibody [EP569Y]; Anti-PDPK1 antibody [EP569Y] at 1/1000 dilution + 293 cell lysate.Predicted band size : 63 kDa.Observed band size : 63 kDa.
IHC Image
Immunohistochemistry (Paraffin-embedded sections) - PDPK1 antibody [EP569Y] (1:100) staining human PDPK1 in human prostate carcinoma tissue by immunohistochemistry using paraffin embedded tissue.

 

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