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Anti-HDAC4 Antibody Y416
Also for HDAC4 (NM_006037)
|A synthetic peptide corresponding to residues near the N-terminus of human Histone Deacetylase 4 was used as immunogen.|
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:500 - 5,000; ICC: 1:250 - 500
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|IgG fraction (Protein A or G Sepharose)
|Does not react with Mouse, Rat
|Homo sapiens histone deacetylase 4 (HDAC4)|
|AHO3; BDMR; HA6116; HD4; HDAC-4; HDAC-A; HDACA|
|Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq]. |
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Western blot - HDAC4 antibody [Y416]; Anti-HDAC4 antibody [Y416] at 1/5000 dilution + Hela cell lysate.Predicted band size : 119 kDa.Observed band size : 140 kDa .
Immunocytochemistry/ Immunofluorescence - HDAC4 antibody [Y416]; Immunofluorescent staining of HeLa cells using ab32534 at a dilution of 1/250 - 1/500