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Anti-MAP2K5 Antibody EP648Y

WB(1)

IF(1)

Gene Name Homo sapiens mitogen-activated protein kinase kinase 5 (MAP2K5), transcript variant 2 Synonyms: HsT17454; MAPKK5; MEK5; PRKMK5 Immunogen A synthetic peptide corresponding to residues within human MKK5 was used as an immunogen. Buffer 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Clone Name EP648Y Isotype Rabbit IgG Species Reactivity Human Concentration Purification (Protein A or G Sepharose) Guaranteed Application * WB, IF Suggested Dilutions WB: 1:10,000; ICC: 1:100-250 Background The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been described. [provided by RefSeq]. Related Pathway EGFR1 Signaling Pathway Focal Adhesion MAPK signaling pathway

Related Lysate from OriGene • Transient overexpression lysate of mitogen-activated protein kinase kinase 5 (MAP2K5), transcript variant B Anti-Tag Antibodies & WB Reagent • Anti-Tag Antibodies • Western Blot Reagent shRNA • MAP2K5 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector • MAP2K5 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector • Map2k5 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector • MAP2K5 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector • Map2k5 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector Related ORF Clones • Myc-DDK-tagged ORF clone of Homo sapiens mitogen-activated protein kinase kinase 5 (MAP2K5), transcript variant 2 as transfection-ready DNA • Lenti ORF clone of Human mitogen-activated protein kinase kinase 5 (MAP2K5), transcript variant 2 , Myc-DDK-tagged • Lenti ORF clone of Human mitogen-activated protein kinase kinase 5 (MAP2K5), transcript variant 2, mGFP tagged • GFP-tagged ORF clone of Homo sapiens mitogen-activated protein kinase kinase 5 (MAP2K5), transcript variant 2 as transfection-ready DNA Related cDNA Clones • Homo sapiens mitogen-activated protein kinase kinase 5 (MAP2K5), transcript variant 2 as transfection-ready DNA • Kinase deficient mutant (K195M) of Homo sapiens mitogen-activated protein kinase kinase 5 (MAP2K5), transcript variant B as transfection-ready DNA • Kinase deficient mutant (K195M) of Homo sapiens mitogen-activated protein kinase kinase 5 (MAP2K5), transcript variant B as transfection-ready DNA

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

• HRP
• Biotin
• PE
• FITC
• DyLight® 488
• DyLight® 550
• DyLight® 594
• DyLight® 633

* DyLight is a trademark of Thermo-Fisher Scientific

Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)