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Anti-PLCB3 PHOSPHO Antibody EPR1498Y
Also for PLCB3 (NM_000932)
|A phosphor-specific peptide corresponding to residues surrounding Serine 1105 of human PLC-?3 was used as an immunogen. This antibody detects PLC- ?3 phosphorylated on Ser1105.|
||Tissue culture supernatant
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:5000
|Does not react with Mouse, Rat. Is unsuitable for Flow Cyt,ICC/IF,IHC-Fr,IHC-P or IP.|
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
|Is unsuitable for Flow Cyt,ICC/IF,IHC-Fr,IHC-P or IP.
|Homo sapiens phospholipase C, beta 3 (phosphatidylinositol-specific) (PLCB3), transcript variant 1|
|PLCB3 plays an important role in initiating receptor-mediated signal transduction. Activation of PLC takes place in many cells as a response to stimulation by hormones, growth factors, neurotransmitters, and other ligands (Lagercrantz et al., 1995 [PubMed 7607669]).[supplied by OMIM]. |
Signaling by GPCR
Wnt Signaling Pathway
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Western blot - Phospholipase C beta 3 (phospho S1105) antibody [EPR1498Y]; All lanes : Anti-Phospholipase C beta 3 (phospho S537) antibody [EPR1498Y] at 1/2000 dilution.Lane 1 : HeLa cell lysate, untreated.Lane 2 : HeLa cell lysate, treated with TPA.Lysates/proteins at 10 µg per lane.Secondary.Goat anti-rabbit HRP labeled at 1/2000 dilution.Predicted band size : 139 kDa.Observed band size : 150 kDa .