NFE2 (MIM 601490), NFE2L1 (MIM 163260), and NFE2L2 comprise a family of human genes encoding basic leucine zipper (bZIP) transcription factors. They share highly conserved regions that are distinct from other bZIP families, such as JUN (MIM 165160) and FOS (MIM 164810), although remaining regions have diverged considerably from each other (Chan et al., 1995 [PubMed 7868116]).[supplied by OMIM].
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Western blot analysis on A) untreated and B) AP treated HepG2 cell lysates using anti-Phospho-Nrf2 (pS40) RabMAb (TA303614), 1:20,000 dilution.<br> Pan control: C) untreated and D) AP untreated HepG2 cell lysates using anti-LDL Receptor RabMAb (cat#