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Anti-MMP9 Antibody EP1255Y
Also for MMP9 (NM_004994)
|A synthetic peptide corresponding to residues near the C-terminus of human MMP-9 was used as an immunogen.|
||Tissue culture supernatant
|Mouse, Rat, Dog, Human
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:10000; IHC-P: 1:100 - 1:250; ICC/IF: 1:250 - 1:500; FC: 1:20
|Preservative: 0.01% Sodium azide; Constituents: 50% Glycerol, 0.05% BSA|
|Tissue culture supernatant
|Is unsuitable for IP.
|Homo sapiens matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (MMP9)|
|CLG4B; GELB; MANDP2; MMP-9|
Entrez Gene 4318 Human
Entrez Gene 17395 Mouse
Entrez Gene 81687 Rat
Entrez Gene 403885 Dog
|Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. [provided by RefSeq]. |
|ProteaseDruggable Genome Leukocyte transendothelial migrationPathways in cancerBladder cancer|
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Western blot - Anti-MMP9 antibody; Anti-MMP9 antibody [EP1255Y] at 1/1000 dilution + U937 cell lysate at 10 ug.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 78 kDa.Observed band size : 64,82,92 kDa .
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MMP9 antibody; Immunohistochemical analysis of paraffin-embedded Human lymphoma tissue labelling MMP9 with TA303601 at 1/100 dilution.