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Home Antibody All anti-LIMS1 antibodies

Anti-LIMS1 Antibody EP1943Y

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303580
  • Rabbit monoclonal antibody against LIMS1 (EP1943Y )
  • FREE positive control: HEK293T cell transient overexpression lysate (LC417616) , 20ug
100ul 325 3-7 Days
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WB(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues within LIM zinc-binding 3 region of human LIMS1 was used as an immunogen.
Clone NameEP1943Y IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:5000; FC: 1:20
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for ICC,IHC-P or IP.

Reference Data

Target NameHomo sapiens LIM and senescent cell antigen-like domains 1 (LIMS1), transcript variant 2
Alternative NamePINCH; PINCH-1; PINCH1
Database LinkNP_004978
FunctionThe protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. [provided by RefSeq].
Related Pathway

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WB Image
Western blot - LIMS1 antibody [EP1943Y]; All lanes : Anti-LIMS1 antibody [EP1943Y] at 1/5000 dilution.Lane 1 : Jurkat cell lysate.Lane 2 : K562 cell lysate.Lane 3 : HeLa cell lysate.Lane 4 : 293 cell lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 37 kDa.Observed band size : 34-37 kDa .

 

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