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Home Antibody All anti-UBE2K antibodies

Anti-UBE2K Antibody EP1145Y

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SKU Description Amount Price Availability*  
TA303536
  • Rabbit monoclonal antibody against UBC-1(EP1145Y)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC417371) , 20ug Explanation
100ul $325 3-7 Days
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WB(1)
IHC(1)
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Also for UBE2K (NM_005339)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues of human UBC1 was used as an immunogen.
Clone NameEP1145Y IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:5000; IHC: 1:250 500; ICC: 1:250; IP: 1:50
Predicted MW Explanation 22 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant

Reference Data

Target NameHomo sapiens ubiquitin-conjugating enzyme E2K (UBE2K), transcript variant 1
Alternative NameE2-25K; HIP2; HYPG; LIG; UBC1
Database LinkNP_005330
Entrez Gene 3093 Human
Entrez Gene 53323 Mouse
Entrez Gene 289623 Rat
FunctionThe protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq].
Related PathwayTranscription FactorsDruggable Genome Ubiquitin mediated proteolysis

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - HIP2 antibody [EP1145Y]; Anti-HIP2 antibody [EP1145Y] at 1/100000 dilution + Daudi cell lysate at 10 ug.Secondary.Goat anti-Rabbit HRP labeled at 1/2000 dilution.Predicted band size : 22 kDa.Observed band size : 24 kDa .
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Immunohistochemistry (Paraffin-embedded sections) - HIP2 antibody [EP1145Y]; Ab52930 (1:250) staining human HIP2 in human liver tissue by immunohistochemistry using paraffin embedded tissue.
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