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Home Antibody All anti-UBE2K antibodies

Anti-UBE2K Antibody EP1145Y

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303536
  • Rabbit monoclonal antibody against UBC-1(EP1145Y)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC417371) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(1)
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Also for UBE2K (NM_005339)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues of human UBC1 was used as an immunogen.
Clone NameEP1145Y IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:5000; IHC: 1:250 500; ICC: 1:250; IP: 1:50
Predicted MW Explanation 22 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant

Reference Data

Target NameHomo sapiens ubiquitin-conjugating enzyme E2K (UBE2K), transcript variant 1
Alternative NameE2-25K; HIP2; HYPG; LIG; UBC1
Database LinkNP_005330
Entrez Gene 3093 Human
Entrez Gene 53323 Mouse
Entrez Gene 289623 Rat
FunctionThe protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq].
Related PathwayTranscription FactorsDruggable Genome Ubiquitin mediated proteolysis

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - HIP2 antibody [EP1145Y]; Anti-HIP2 antibody [EP1145Y] at 1/100000 dilution + Daudi cell lysate at 10 ug.Secondary.Goat anti-Rabbit HRP labeled at 1/2000 dilution.Predicted band size : 22 kDa.Observed band size : 24 kDa .
IHC Image
Immunohistochemistry (Paraffin-embedded sections) - HIP2 antibody [EP1145Y]; Ab52930 (1:250) staining human HIP2 in human liver tissue by immunohistochemistry using paraffin embedded tissue.

 

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