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Anti-GSN Antibody EPR1941Y
|A synthetic peptide corresponding to residues in the N-terminal region of human Gelsolin was used as immunogen.|
||Tissue culture supernatant
|Human (Does not react with: Mouse, Rat)
||Lot dependent; please refer to CoA along with shipment
|WB, IHC, IF
||WB: 1:25000 - 1:50000; IP: 1:50; IHC-P: 1:100 - 1:250; ICC: 1:100 - 1:250
|Does not react with Mouse, Rat. Is unsuitable for Flow Cyt.|
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
|Is unsuitable for Flow Cyt.
|Homo sapiens gelsolin (GSN), transcript variant 1|
Entrez Gene 2934 Human
|The protein encoded by this gene binds to the 'plus' ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq]. |
|Secreted ProteinDruggable Genome Fc gamma R-mediated phagocytosisRegulation of actin cytoskeleton|
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Western blot - Gelsolin antibody [EPR1941Y]; Anti-Gelsolin antibody [EPR1941Y] at 1/50000 dilution + human plasma at 10 ug.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 86 kDa.Observed band size : 90 kDa .
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Gelsolin antibody [EPR1941Y]; TA303531 at 1/100 dilution staining Gelsolin in human colon tissue, using a HRP/AP polymerized secondary antibody.
Immunocytochemistry/ Immunofluorescence - Anti-Gelsolin antibody [EPR1941Y]; TA303531 staining Gelsolin in human SH-SY5Y cells by Immunocytochemistry/ Immunofluorescence.