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Home All anti-FOLH1 antibodies

Anti-FOLH1 Antibody EP3253

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA303519
  • Rabbit monoclonal antibody against PSMA (EP3253 )
  • FREE positive control: HEK293T cell transient overexpression lysate (LC423102) , 20ug
100µl $325 In Stock
TA802519S
  • Purified GAPDH mouse monoclonal antibody (Loading control), clone 2D9
30ul
$100
$50*
In Stock
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* Buy one primary antibody, get 50% off a GAPDH loading control antibody.
WB(1)
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Also for FOLH1 (NM_001014986)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the N-terminus of human PSMA was used as an immunogen.
Clone NameEP3253 IsotypeRabbit IgG
Species ReactivityHuman Concentration
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 -5000; FC: 1:60; IP: 1:10
Buffer50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.

Reference Data

Target NameHomo sapiens folate hydrolase (prostate-specific membrane antigen) 1 (FOLH1), transcript variant 2
Alternative NameFGCP; FOLH; GCP2; GCPII; mGCP; NAALAD1; NAALAdase; PSM; PSMA
Database LinkNP_001014986
FunctionThis gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants. [provided by RefSeq].
Related Pathway

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WB Image
Western blot analysis on LnCaP cell lysate using anti-PSMA RabMAb (TA303519), dilution 1:5000.

 

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