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Home Antibody All anti-ERBB4 antibodies

Anti-ERBB4 Antibody EP192Y


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA303502 Rabbit monoclonal antibody against HER4 / c-ErbB4 (EP192Y ) 100ul $325 In Stock
LC421001 ERBB4 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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Also for ERBB4 (NM_001042599)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenA synthetic peptide near the C-terminus (cytoplasmic domain) of human Her4/ErbB4 was used as immunogen.
Clone NameEP192Y IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:2000
Predicted MW Explanation 147 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,ICC,IHC-P or IP.

Reference Data

Target NameHomo sapiens erb-b2 receptor tyrosine kinase 4 (ERBB4), transcript variant JM-a/CVT-2
Alternative NameALS19; HER4; p180erbB4
Database LinkNP_001036064
Entrez Gene 2066 Human
Entrez Gene 13869 Mouse
Entrez Gene 59323 Rat
FunctionThis gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq].
Related PathwayProtein KinaseTransmembraneDruggable Genome ErbB signaling pathwayCalcium signaling pathwayEndocytosis

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - ErbB 4 antibody [EP192Y]; Anti-ErbB 4 antibody [EP192Y] at 1/2000 dilution + human brain tissue lysate at 10 ug.Secondary.Goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 147 kDa.Observed band size : 185 kDa .


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