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Anti-CCR8 Antibody E77
Also for CCR8 (NM_005201)
|A synthetic peptide corresponding to residues in loop2 extracellular domain of human CKR8 was used as immunogen. The antibody does not cross-react with other G-protein coupled receptor 1 family members.|
||Tissue culture supernatant
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:2000; IP: 1:25; FC: 1:20; ICC/IF: 1:250
|Does not react with Mouse. Is unsuitable for IHC.|
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05% (Protein A or G Sepharose)
|Is unsuitable for IHC.
|Homo sapiens chemokine (C-C motif) receptor 8 (CCR8)|
|CC-CKR-8; CCR-8; CDw198; CKRL1; CMKBR8; CMKBRL2; CY6; GPRCY6; TER1|
|This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region. [provided by RefSeq]. |
Cytokine-cytokine receptor interaction
Signaling by GPCR
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Western blot - CCR8 antibody [E77]; All lanes : Anti-CCR8 antibody [E77] at 1/2000 dilution.Lane 1 : 10ug Jurkat cell lysate.Lane 2 : 10ug K562 cell lysate.Predicted band size : 41 kDa.Observed band size : 41 kDa.
Immunofluorescence - CCR8 antibody [E77]; Immunofluorescent staining of HeLa cells using ab32399 at 1:250 dilution.