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Anti-CASP7 Antibody Y33
Also for CASP7 (NM_033339)
|A synthetic peptide corresponding to N-terminal residues of human Pro-Caspase-7 was used as immunogen. The antibody only recognizes the pro-form of Caspase-7. It does not react with the cleaved forms (active enzyme) of Caspase-7.|
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1,000; IHC: 1:50; ICC: 1:50
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Does not react with Mouse, Rat
|Homo sapiens caspase 7, apoptosis-related cysteine peptidase (CASP7), transcript variant c|
|CASP-7; CMH-1; ICE-LAP3; LICE2; MCH3|
|This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of this caspase is cleaved by caspase 3 and 10. It is activated upon cell death stimuli and induces apoptosis. Alternative splicing results in four transcript variants, encoding three distinct isoforms. [provided by RefSeq]. |
MAPK signaling pathway
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Western blot - pro Caspase 7 antibody [Y33]; Anti-pro Caspase 7 antibody [Y33] at 1/1000 dilution + Jurkat cell lysate.Predicted band size : 34 kDa.Observed band size : 34 kDa.
Immunohistochemistry (Paraffin-embedded sections) - pro Caspase 7 antibody [Y33]; Immunohistochemical analysis of paraffin-embedded human lung squamous carcinoma using ab32067 at 1/50 dilution.