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Home Antibody All anti-CASP7 antibodies

Anti-CASP7 Antibody Y33

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303418
  • Rabbit monoclonal antibody against Caspase-7 (pro)(Y33)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC409592) , 20ug
100ul 325 3-7 Days
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WB(1)
IHC(1)
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Also for CASP7 (NM_033339)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to N-terminal residues of human Pro-Caspase-7 was used as immunogen. The antibody only recognizes the pro-form of Caspase-7. It does not react with the cleaved forms (active enzyme) of Caspase-7.
Clone NameY33 IsotypeIgG
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1,000; IHC: 1:50; ICC: 1:50
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens caspase 7, apoptosis-related cysteine peptidase (CASP7), transcript variant c
Alternative NameCASP-7; CMH-1; ICE-LAP3; LICE2; MCH3
Database LinkNP_203125
FunctionThis gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of this caspase is cleaved by caspase 3 and 10. It is activated upon cell death stimuli and induces apoptosis. Alternative splicing results in four transcript variants, encoding three distinct isoforms. [provided by RefSeq].
Related Pathway
Apoptosis
MAPK signaling pathway

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WB Image
Western blot - pro Caspase 7 antibody [Y33]; Anti-pro Caspase 7 antibody [Y33] at 1/1000 dilution + Jurkat cell lysate.Predicted band size : 34 kDa.Observed band size : 34 kDa.
IHC Image
Immunohistochemistry (Paraffin-embedded sections) - pro Caspase 7 antibody [Y33]; Immunohistochemical analysis of paraffin-embedded human lung squamous carcinoma using TA303418 at 1/50 dilution.

 

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