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Anti-ACACA PHOSPHO Antibody EP1885Y
Also for ACACA (NM_198835)
|A phospho specific peptide corresponding to residues surrounding serine 79 of human ACC1 was used as an immunogen. This antibody detects ACC1 phosphorylated at serine 79.|
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:5000; ICC: 1:100 - 250
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
|Tissue culture supernatant
|Does not react with Mouse, Rat
|Homo sapiens acetyl-Coenzyme A carboxylase alpha (ACACA), transcript variant 7|
|ACC, ACAC, ACC1, ACCA|
|Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq]. |
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Western blot - Acetyl Coenzyme A Carboxylase (phospho S79) antibody [EP1885Y]; All lanes : Anti-Acetyl Coenzyme A Carboxylase (phospho S79) antibody [EP1885Y] at 1/10000 dilution.Lane 1 : A431 cell lysate, untreated.Lane 2 : A431 cell lysate, treated with LP.Lysates/proteins at 10 µg per lane.Secondary.HRP conjugated Goat anti-rabbit at 1/2000 dilution.Predicted band size : 265 kDa.Observed band size : >250 kDa .