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Home Antibody All anti-ACACA antibodies

Anti-ACACA PHOSPHO Antibody EP1885Y

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303375
  • Rabbit monoclonal antibody against Acetyl CoA Carboxylase 1 (ACC1) Phos. (pS79) (EP1885Y ) (phospho-specific)
100ul 325 3-7 Days
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OriGene Data

ImmunogenA phospho specific peptide corresponding to residues surrounding serine 79 of human ACC1 was used as an immunogen. This antibody detects ACC1 phosphorylated at serine 79.
Clone NameEP1885Y IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:5000; ICC: 1:100 - 250
Predicted MW Explanation 265 kDa
BufferpH: 7.40
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens acetyl-Coenzyme A carboxylase alpha (ACACA), transcript variant 7
Alternative NameACC, ACAC, ACC1, ACCA
Database LinkNP_942132
Entrez Gene 31 Human
FunctionAcetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq].
Related PathwayDruggable Genome Fatty acid biosynthesisPyruvate metabolismPropanoate metabolismMetabolic pathwaysInsulin signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Acetyl Coenzyme A Carboxylase (phospho S79) antibody [EP1885Y]; All lanes : Anti-Acetyl Coenzyme A Carboxylase (phospho S79) antibody [EP1885Y] at 1/10000 dilution.Lane 1 : A431 cell lysate, untreated.Lane 2 : A431 cell lysate, treated with LP.Lysates/proteins at 10 ug per lane.Secondary.HRP conjugated Goat anti-rabbit at 1/2000 dilution.Predicted band size : 265 kDa.Observed band size : >250 kDa .

 

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