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Home Antibody All anti-BIN1 antibodies

Anti-BIN1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303366
  • Goat Polyclonal Antibody against BIN1
100ug 325 3-7 Days
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WB(1)
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Also for BIN1 (NM_004305)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

Immunogen Peptide with sequence C-SDNAPAKGNKSPS, from the internal region of the protein sequence according to NP_004296.1; NP_647593.1; NP_647594.1; NP_647595.1; NP_647596.1; NP_647597.1; NP_647598.1; NP_647599.1; NP_647600.1; NP_647601.1.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human. Expected from seq similarity: Human, Mouse, Rat, Dog, Pig, Cow Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsELISA: 1:1,000. WB: 1-3µg/ml.
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Reference Data

Target NameHomo sapiens bridging integrator 1 (BIN1), transcript variant 8
Alternative NameAMPH2; AMPHL; SH3P9
Database LinkNP_004296
Entrez Gene 274 Human
Entrez Gene 30948 Mouse
Entrez Gene 117028 Rat
Entrez Gene 483870 Dog
FunctionThis gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynanim, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in ten transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described. [provided by RefSeq].
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
TA303366 (0.1µg/ml) staining of Human Skeletal Muscle lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence

 

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