Home Antibody All anti-FZD4 antibodies
Also for FZD4 (NM_012193)
| Peptide with sequence DEEERRCDPIRIS, from the internal region of the protein sequence according to NP_036325.2.|
|Test: Human. Expected from seq similarity: Human, Rat
||ELISA: 1:16,000. WB: 0.3-1µg/ml.
|Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.|
| Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
|Homo sapiens frizzled class receptor 4 (FZD4)|
|CD344; EVR1; FEVR; Fz-4; Fz4; FZD4S; FzE4; GPCR; hFz4|
Entrez Gene 8322 Human
Entrez Gene 64558 Rat
|This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. [provided by RefSeq]. |
|GPCRTransmembraneDruggable Genome Wnt signaling pathwayMelanogenesisPathways in cancerColorectal cancerBasal cell carcinoma|
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TA303333 (1µg/ml) staining of Small Intestine (Ileum) cell lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.